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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: Ann Allergy Asthma Immunol. 2021 Mar 11;127(1):19–27. doi: 10.1016/j.anai.2021.03.005

Table 1.

Immunoglobulin standards used in evaluation of suspected CVID.

Cut off for Immunoglobulins 2 Standard deviation below the mean by Age and Gender (g/L)

Male Female
Age IgG IgA IgM IgG IgA IgM
4 5.1 0.36 0.35 5.3 0.33 0.42
7 6 0.48 0.37 5.9 0.44 0.45
10 6.6 0.57 0.38 6.4 0.52 0.48
14 6.6 0.64 0.4 6.8 0.62 0.5
18 6.5 0.68 0.41 6.9 0.69 0.52
20 6.5 0.71 0.41 6.9 0.71 0.53
30 6.5 0.8 0.43 6.8 0.75 0.57
40 6.6 0.87 0.42 6.7 0.78 0.55
50 6.6 0.93 0.4 6.6 0.81 0.49
60 6.7 0.98 0.39 6.5 0.85 0.45
70 6.8 1.03 0.38 6.5 0.9 0.42
80 6.9 1.07 0.37 6.5 0.96 0.39
*

Adapted from Reference distributions for immunoglobulins A, G, and M: A comparison of a large cohort to the world's literature.77