Table 1.
Immunoglobulin standards used in evaluation of suspected CVID.
Cut off for Immunoglobulins 2 Standard deviation below the mean by Age and Gender (g/L)
Male | Female | |||||
---|---|---|---|---|---|---|
Age | IgG | IgA | IgM | IgG | IgA | IgM |
4 | 5.1 | 0.36 | 0.35 | 5.3 | 0.33 | 0.42 |
7 | 6 | 0.48 | 0.37 | 5.9 | 0.44 | 0.45 |
10 | 6.6 | 0.57 | 0.38 | 6.4 | 0.52 | 0.48 |
14 | 6.6 | 0.64 | 0.4 | 6.8 | 0.62 | 0.5 |
18 | 6.5 | 0.68 | 0.41 | 6.9 | 0.69 | 0.52 |
20 | 6.5 | 0.71 | 0.41 | 6.9 | 0.71 | 0.53 |
30 | 6.5 | 0.8 | 0.43 | 6.8 | 0.75 | 0.57 |
40 | 6.6 | 0.87 | 0.42 | 6.7 | 0.78 | 0.55 |
50 | 6.6 | 0.93 | 0.4 | 6.6 | 0.81 | 0.49 |
60 | 6.7 | 0.98 | 0.39 | 6.5 | 0.85 | 0.45 |
70 | 6.8 | 1.03 | 0.38 | 6.5 | 0.9 | 0.42 |
80 | 6.9 | 1.07 | 0.37 | 6.5 | 0.96 | 0.39 |
Adapted from Reference distributions for immunoglobulins A, G, and M: A comparison of a large cohort to the world's literature.77