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. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: Biomed Pharmacother. 2021 May 25;140:111753. doi: 10.1016/j.biopha.2021.111753

Table 3.

Exosomal miRNAs in stroke.

Cargo (s) Detection methods Effect (s) References
miR-17–92 Increases neural plasticity and functional recovery after stroke, possibly via targeting phosphatase and tensin homolog. [253]
MiR-133b promotes neural plasticity and functional recovery after treatment of stroke [254]
miR-133b improve neural plasticity and functional recovery after stroke [255]
MiR-30d-5p Prevent cerebral injury by inhibiting autophagy-mediated microglial polarization to M1. [256]
MiR-126 Promotes neurorestorative effects in T2DM mice. [257]
miR-181c-3p Inhibits Neuroinflammation by Downregulating CXCL1 in Astrocytes. [258]
miR-138-5p Reduces neurological impairment by promoting proliferation and inhibiting inflammatory responses of astrocytes following IS by targeting LCN2. [259]
miR-124 Promotes Neurogenesis [260]
microRNA-26a Enhanced neurogenesis after ischemic stroke. [261]
miR-146b Improve neurological injury after ischemic stroke. [242]
MicroRNA-17-92 Enhance Neuroplasticity and Functional Recovery After Stroke. [262]
miR-146a-5p Inhibiting Neuronal Apoptosis and Microglial M1 Polarization. [237]
miR-124 Cortical neurogenesis is increased. [263]
miR-134 It enhanced expressing LIM domain kinase to increase plasticity of synaptic-dendritic after Ischemic stroke. [264]