Table 3.
Exosomal miRNAs in stroke.
| Cargo (s) Detection methods | Effect (s) | References |
|---|---|---|
| miR-17–92 | Increases neural plasticity and functional recovery after stroke, possibly via targeting phosphatase and tensin homolog. | [253] |
| MiR-133b | promotes neural plasticity and functional recovery after treatment of stroke | [254] |
| miR-133b | improve neural plasticity and functional recovery after stroke | [255] |
| MiR-30d-5p | Prevent cerebral injury by inhibiting autophagy-mediated microglial polarization to M1. | [256] |
| MiR-126 | Promotes neurorestorative effects in T2DM mice. | [257] |
| miR-181c-3p | Inhibits Neuroinflammation by Downregulating CXCL1 in Astrocytes. | [258] |
| miR-138-5p | Reduces neurological impairment by promoting proliferation and inhibiting inflammatory responses of astrocytes following IS by targeting LCN2. | [259] |
| miR-124 | Promotes Neurogenesis | [260] |
| microRNA-26a | Enhanced neurogenesis after ischemic stroke. | [261] |
| miR-146b | Improve neurological injury after ischemic stroke. | [242] |
| MicroRNA-17-92 | Enhance Neuroplasticity and Functional Recovery After Stroke. | [262] |
| miR-146a-5p | Inhibiting Neuronal Apoptosis and Microglial M1 Polarization. | [237] |
| miR-124 | Cortical neurogenesis is increased. | [263] |
| miR-134 | It enhanced expressing LIM domain kinase to increase plasticity of synaptic-dendritic after Ischemic stroke. | [264] |