Figure 2. Microbial taxa are associated with natural genetic variation in C. elegans gut microbiome types.

A. Box-whisker plot of enrichment factors for microbial taxa for 38 C. elegans strains on day 3 adulthood colored by microbiome types. Enrichment factors for each microbial taxa were generated by log 2 transformation of fold changes of relative abundance in worm samples to BIGbiome lawn. B. Bar plot of commonality for each microbial taxa is calculated as the percentage of worm strains that was colonized by the corresponding microbial taxon at a minimum threshold of 0.01% in relative abundance. See also Data S1AB. C. GWAS analyses identify genetic loci that are associated with gut microbiome abundance. GWAS plot for traits of absolute abundance of specific microbiome members. Points represent significance and genome region and are colored by microbe. Dashed lines indicate genomic region enriched for microbe-specific trait and are similarly colored by microbe. D. GWAS plot for traits of relative abundance of specific microbiome members. Points represent significance and genome region and are colored by microbe. Dashed lines indicate genomic region enriched for microbe-specific trait and are similarly colored by microbe. See also Table S2 for a full list of genomic positions and associated microbial taxa.