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. 2021 Jun 23;6:88. doi: 10.1038/s41541-021-00344-1

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — A threshold of >10,000 memory B cells per 10⁶ PBMC can increase the proportion of reactive donors. This criterion would have reduced the number of donors to be subjected to functional evaluation to 46 of 101 donors; 22 (48%) of these PBMC samples would have been repeatedly reactive and the proportion of non-responders in pre-testing could have been reduced from 70 to 52%.