Table 1.
Body weight of chimeric mice was normalized by body weight at 8 week old for comparison.
| Chimeric mice (Chimeric ratio; ICR: R6/2) | Body weight (normalized by 8 week aged) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Weeks of age | ||||||||||||||
| 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | ||
| ICR | 1.0 | 1.0 | 1.1 | 1.1 | 1.2 | 1.3 | 1.4 | 1.3 | 1.4 | 1.4 | 1.5 | 1.6 | 1.6 | |
| ICR | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.1 | 1.1 | 1.1 | 1.1 | 1.0 | 1.1 | 1.1 | |
| ICR | 1.0 | 1.1 | 1.1 | 1.2 | 1.2 | 1.2 | 1.3 | 1.3 | 1.3 | 1.3 | 1.5 | 1.4 | 1.4 | |
| 1 | (90%: 10%) | 1.0 | 1.1 | 1.1 | 1.2 | 1.2 | 1.3 | 1.4 | 1.4 | 1.5 | 1.5 | 1.6 | 1.6 | 1.6 |
| 2 | (90%: 10%) | 1.0 | 1.0 | 1.0 | 1.1 | 1.2 | 1.3 | 1.4 | 1.3 | 1.5 | 1.4 | 1.6 | 1.5 | 1.6 |
| 3 | (90%: 10%) | 1.0 | 1.2 | 1.1 | 1.2 | 1.4 | 1.4 | 1.4 | 1.5 | 1.7 | 1.5 | 1.6 | 1.7 | 1.7 |
| 4 | (90%: 10%) | 1.0 | 1.1 | 1.1 | 1.1 | 1.1 | 1.1 | 1.1 | 1.1 | 1.2 | 1.1 | 1.2 | 1.3 | 1.3 |
| 5 | (70%: 30%) | 1.0 | 1.1 | 1.1 | 1.3 | 1.2 | 1.4 | 1.3 | 1.5 | 1.5 | 1.6 | 1.5 | 1.6 | 1.7 |
| 6 | (70%: 30%) | 1.0 | 1.0 | 1.1 | 1.1 | 1.1 | 1.2 | 1.2 | 1.2 | 1.2 | 1.2 | 1.2 | 1.3 | 1.3 |
| 7 | (50%: 50%) | 1.0 | 1.0 | 1.1 | 1.1 | 1.1 | 1.1 | 1.1 | 1.2 | 1.2 | 1.2 | 1.2 | 1.2 | 1.3 |
| 8 | (50%: 50%) | 1.0 | 1.0 | 1.0 | 1.0 | 1.2 | 1.1 | 1.2 | 1.1 | 1.3 | 1.3 | 1.3 | 1.4 | 1.4 |
| 9 | (50%: 50%) | 1.0 | 1.0 | 1.1 | 1.1 | 1.1 | 1.2 | 1.2 | 1.3 | 1.3 | 1.3 | 1.4 | 1.4 | 1.4 |
| 10 | (40%: 60%) | 1.0 | 1.0 | 1.1 | 1.1 | 1.1 | * | |||||||
| 11 | (40%: 60%) | 1.0 | 1.1 | 1.1 | 1.1 | 1.2 | 1.2 | 1.3 | 1.3 | 1.3 | 1.4 | 1.4 | 1.5 | 1.5 |
| 12 | (30%: 70%) | 1.0 | 1.1 | 1.1 | 1.1 | 1.1 | 1.2 | 1.3 | 1.3 | 1.4 | 1.4 | 1.4 | 1.5 | 1.5 |
| 13 | (20%: 80%) | 1.0 | 1.0 | 1.0 | 1.1 | 1.1 | * | |||||||
| 14 | (10%: 90%) | 1.0 | 1.0 | 1.0 | 1.0 | 0.9 | 0.8 | 0.9 | 0.8 | 0.7 | 0.7 | 0.6 | X | |
| 15 | (10%: 90%) | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.1 | 0.9 | 0.9 | 0.7 | 0.8 | 0.7 | 0.7 | 0.6 |
| 16 | (10%: 90%) | 1.0 | 1.0 | 1.0 | 1.1 | 1.0 | 1.1 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 0.9 | 0.9 |
| 17 | (10%: 90%) | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.1 | 1.0 | 1.0 | 0.9 | 0.9 | 0.7 | 0.7 |
| 18 | (0: 100%) | 1.0 | 1.1 | 1.1 | 1.2 | X | ||||||||
| 19 | (0: 100%) | 1.0 | 1.0 | 0.9 | 0.9 | 0.9 | * | |||||||
The chimeric ratio was estimated from their coat color. Chimeric mice #10, #13, and #19 (*) were used for sampling at 12 weeks of age. Chimeric mice #14 and #18 were dead at 11 and 19 weeks of age, respectively.