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. 2021 Jun 23;11:13192. doi: 10.1038/s41598-021-92335-4

Figure 3.

Figure 3

Sensitivity and specificity analysis. Gene panel based on the top 10 most significant genes by adjusted p-value. The 95th centile is calculated for each gene using the outputs of Non and Focal-PNI samples. The 95th centile score is subtracted from each sample. Fields that are positive (i.e. > 95th centile) are given a score of 1 and are shaded orange. The total score is then calculated across all 10 genes to give a combined score out of 10. Outliers (shaded blue) are determined as any Non or Focal-PNI samples with a score of > 1, or Extensive PNI with a Score < 2.