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. 2021 Jun 23;11:13139. doi: 10.1038/s41598-021-92576-3

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Mediation model of associations between environmental mastery and total ceramides, and possible mediation by sleep quality (PSQI) and BMI. Only participants with data for all variables were included, n = 913. Standardized regression coefficient and standard errors (in parentheses) of the multivariate linear regressions are presented. The paths affecting total ceramides (b and c) controlled for sex, age, educational level, depression (CESD), and medication usage (corticosteroids, cholesterol-lowering, antihypertensive and antidepressants). The direct path coefficient (c’) indicates the effect of environmental mastery on total ceramide levels adjusting for BMI and sleep quality, while the c path coefficient refers to the effect of environmental mastery on total ceramides without adjustments for mediators. The r value indicates Pearson correlation coefficient between BMI and sleep (PSQI). *p < 0.05, **p < 0.01, ***p < 0.001. ^ns, not significant.