Table 1.

Prediction of drug target and distance information by top10 (FDR < 0.1).

Sig-drug	Proximity	FDR	Targets
Carfilzomib	− 4.769	0.00	ABCB1, PSMB5, PSMB1, PSMB2, PSMB8, PSMB9, PSMB10
Afatinib	− 4.737	0.02	EGFR, ABCB1, ABCG2, ERBB4
Prednisolone acetate	− 4.989	0.02	ABCB1, SLCO1A2, NR3C1, SERPINA6
Isosorbide	− 4.989	0.03	BCL2, BCL2L1, MCL1
Arsenic trioxide	− 4.557	0.04	CYP3A4, TXNRD1, AKT1, JUN, IKBKB, MAPK3, CCND1, MAPK1, CDKN1A, HDAC1, PML
Vorinostat	− 4.638	0.04	HDAC2, HDAC1, HDAC8, HDAC3, HDAC6, ACUC1
Tucatinib	− 4.516	0.05	ABCB1, ABCG2, SLC22A2, CYP2C8, SLC47A1, SLC47A2, ERBB3
Tazemetostat	− 4.656	0.05	ABCB1, ABCG2, SLC47A1, SLC47A2, EZH2, EZH1
Avapritinib	− 4.611	0.05	ABCB1, ABCG2, KIT
Tixocortol	− 4.989	0.09	HDAC2, NR3C1