Table 1.
Values of arterial gas and physiological parameters at baseline, at end of HI insult, and at 60 min, 180 min, and 360 min after insult.
| Baseline | End of insult | 60 min after HI insult | 180 min after HI insult | 360 min after HI insult | |
|---|---|---|---|---|---|
| pH | 7.46 (0.07) | 6.90 (0.11)**** | 7.32 (0.08)**** | 7.48 (0.07) | 7.48 (0.09) |
| PaCO2 (mmHg) | 41.7 (6.2) | 31.2 (7.4)**** | 40.2 (11.3) | 41.5 (9.3) | 42.0 (10.9) |
| PaO2 (mmHg) | 104.0 (22.2) | 16.3 (5.1)**** | 99.2 (23.8) | 89.8 (20.4) | 98.1 (22.4) |
| Base excess (mmol/L) | 5.00 (2.2) | − 25.7 (3.6)**** | − 5.8 (2.6)**** | 6.2 (2.4) | 6.6 (2.5)* |
| Blood glucose (mg/dL) | 152.5 (39.6) | 229.9 (99.8)** | 220.4 (68.4)**** | 189.3 (64.9)* | 177.5 (43.9)* |
| Lactate (mg/dL) | 21.4 (17.9) | 209.1 (29.7)**** | 110.9 (27.1)**** | 38.1 (20.0)* | 32.7 (13.2) |
| Hemoglobin (g/dL) | 9.6 (1.8) | 9.9 (1.8) | 9.9 (1.6) | 10.0 (1.7)* | 9.8 (1.8) |
| Rectal temperature (°C) | 37.9 (0.7) | 37.3 (0.8) | 37.8 (0.9) | 38.0 (0.6) | 38.1 (0.6) |
Values are shown as means (standard deviation).
HI hypoxic–ischemic, pH arterial pH, PaCO2 arterial PCO2, PaO2 arterial PO2.
*p < 0.05; **p < 0.01; ***p < 0.001; **** p < 0.0001 versus baseline by one-way ANOVA, a post hoc analysis with Dunnett's multiple comparison test. One piglet missed blood glucose and lactate data at 6 h after HI insult, two piglets missed rectal temperature baseline data.