Table 1.
Patient characteristics.
| Characteristics | Case 1 | Case 2 | Case 3 | Case 4 | Case 5 | Case 6 | Case 7 | Case 8 |
|---|---|---|---|---|---|---|---|---|
| Sex | Female | Male | Male | Male | Male | Female | Male | Female |
| Age | 15 6/12 | 2 4/12 | 12 0/12 | 8 3/12 | 14 7/12 | 10 5/12 | 18 7/12 | 9 2/12 |
| Ethnicity | Central European | Central European | Central European | Arabian origin | Indian origin | Arabian origin | Central European | African |
| Days in the PICU | 7 | 0 | 7 | 0 | 2 | 28 | 4 | 9 |
| Days in the hospital | 11 | 11 | 15 | 16 | 10 | 54 | 9 | 15 |
| Presenting symptoms | ||||||||
| No. of days with fever before admission | 6 | 1 | 5 | 3 | 4 | 0 | 6 | 5 |
| Abdominal pain | Yes | No | Yes | Yes | Yes | Yes | No | Yes |
| Signs of appendicitis | Yes | No | Yes | Yes | No | No | No | No |
| Emesis | Yes | No | Yes | Yes | No | No | No | Yes |
| Diarrhea | Yes | No | Yes | No | Yes | No | No | Yes |
| Testicular pain | No | No | No | Yes | No | |||
| Febrile seizure | No | Yes | No | No | No | No | No | No |
| Dry cough | No | Yes | Yes | No | No | No | No | No |
| Sore throat | No | No | No | No | No | No | Yes | Yes |
| Headache | No | No | No | No | No | No | No | Yes |
| History of acute SARS-CoV-2 infection | ||||||||
| History of acute SARS-CoV-2 infection (including positive test result) | No | No | No | Yes−4 weeks prior to admission, fever, sore throat | No | No | Yes−3 weeks prior to admission, asymptomatic | Yes−2 weeks prior to admission |
| History of acute SARS-CoV-2 infection in the family | Brother tested positive 1.5 months prior to admission | No | Parents tested positive 2–3 weeks prior to admission | No | Father and sister tested positive 1.5 months prior to admission | No | No | No |
| Laboratory values before the start of treatment | ||||||||
| WBC (4.8–12.0 G./l) | 13.8 | 7 | 14.5 | 9.2 | 7.9 | 12.5 | 9.5 | 15.9 |
| Neutrophils (rel. 33–74%) | 88.8 | 76.2 | 92 | 91.4 | 85 | 87.5 | 85.5 | 95.6 |
| Lymphocytes (rel. 22–51%) | 9 | 14.4 | 4 | 4.6 | 4 | 5.4 | 6.9 | 1.7 |
| Platelets (180–415 G./l) | 70 | 116 | 92 | 80 | 20 | 146 | 128 | 155 |
| Ferritin (7–140 μg/l) | 447 | 413 | 827 | 665 | 378 | 162 | 1,250 | 611 |
| ESR | 108/129 | 30/53 | Not done | 40/65 | 65/90 | Not done | 66/91 | >119 in 1 h |
| CRP (mg/l) | 200 | 90 | 478.8 | 249.6 | 229.7 | 215 | 205.6 | 398.4 |
| IL-6 (pg/ml) | 309.6 | 212.8 | >5,000 | 291.8 | 1,591 | 1,198 | 18.8 | 1,546 |
| Procalcitonin (ng/ml) | 5.18 | Not done | 142.8 | 10.89 | 47.53 | 17.5 | 10.8 | 39.8 |
| D-dimer (<0.5 mg/l) | 2.76 | 5.55 | 15.38 | 4.4 | 5.91 | 2.67 | 4.6 | 4.4 |
| Hs-Trop-I (<53.7 ng/l) | 1,433.1 | neg | 480.6 | 34.7 | 1,124.5 | 20,308 | 258.2 | 264 |
| Pro-BNP (<155 ng/l) | 8,997 | 5,999 | 88,759 | 3,099 | 10,739 | 24,580 | 15,293 | 89,367 |
| Albumin (41–48 g/l) | 22 | 31 | 18 | 26 | 19 | 16 | 19 | 23 |
| SARS-CoV-2 RT-PCR | Positive (CT 37), Negative | Negative | Negative | Negative | Negative | Negative | Negative | Negative |
| SARS-CoV-2 IgG antibody U/ml (>15 positive) | 105 | 112 | 80.3 | 121 | 90.9 | 41.9 | 74.9 | 61.2 |
| PICU | Yes | No | Yes | No | Yes | Yes | Yes | Yes |
| Catecholamines | Yes | Yes | Yes | Yes | Yes | Yes | ||
| Nasal high-flow | Yes | Yes | No | No | Yes | Yes | ||
| Invasive ventilation | No | No | No | Yes | No | No | ||
| Outcome 3 weeks after discharge | ||||||||
| Feels well | Yes | Yes | Yes | Yes | Yes | Yes | Yes | Yes |
| Any signs of sequelae | No | No | No | No | No | No | No | No |