TABLE 3.
The values of the chosen inflammatory markers in the preoperative period (Day 0), and the postoperative period (Day 2), the difference between postoperative and preoperative values were listed and compared according to mortality
| Variables | Total patients (n = 388) | Mortality (+) (n = 13) | Mortality (−) (n = 375) | P |
|---|---|---|---|---|
| Preoperative CRP (mg/L) (mean ± SD) | 27.8 ± 36.3 | 66.3 ± 68 | 26.4 ± 34.1 | .008 |
| Postoperative CRP (mg/L) (mean ± SD) | 114.6 ± 78.7 | 183.3 ± 95.2 | 112.2 ± 77.2 | .002 |
| CRP difference (mg/L) (mean ± SD) | 88.8 ± 77.5 | 117 ± 109.6 | 85.8 ± 76.1 | .125 |
| Preoperative ANC (×109/l) (mean ± SD) | 6.5 ± 4 | 8.1 ± 5.5 | 6.4 ± 3.9 | .212 |
| Postoperative ANC (×109/l) (mean ± SD) | 7.6 ± 3.9 | 8.9 ± 5.8 | 7.6 ± 3.8 | .367 |
| ANC difference (×109/l) (mean ± SD) | 1.1 ± 4.5 | 0.9 ± 4.9 | 1.1 ± .4.5 | .798 |
| Preoperative ALC (×109/l) (mean ± SD) | 1.7 ± 0.8 | 1.4 ± 0.5 | 1.7 ± 0.8 | .131 |
| Postoperative ALC (×109/l) (mean ± SD) | 1.3 ± 1.4 | 0.7 ± 0.5 | 1.3 ± .1.4 | <.001 |
| ALC difference (×109/l) (mean ± SD) | −0.5 ± 1.5 | −0.8 ± 0.8 | −0.5 ± 1.5 | .128 |
| Preoperative NLR (mean ± SD) | 4.9 ± 5.3 | 7 ± 5.8 | 4.9 ± 5.3 | .088 |
| Postoperative NLR (mean ± SD) | 7.9 ± 7 | 21 ± 16.7 | 7.5 ± 5.9 | <.001 |
| NLR difference (mean ± SD) | 2.9 ± 7.8 | 14 ± 15.4 | 2.6 ± 7.1 | .001 |
| Preoperative CLR (mg/dL)/(×109/l) (mean ± SD) | 21.1 ± 33.1 | 57.1 ± 64.8 | 19.8 ± 30.9 | .004 |
| Postoperative CLR (mg/dL)/(×109/l) (mean ± SD) | 147.5 ± 363.8 | 978.9 ± 1727 | 118.7 ± 127.7 | <.001 |
Note: P‐value was determined with either Spearman Rho or Mann‐Whitney U test.
Abbreviations: ALC, absolute lymphocyte count; ANC, absolute neutrophil count; CLR, the ratio of C‐reactive protein to lymphocyte count; CRP, C‐reactive protein; NLR, the ratio of neutrophil count to lymphocyte count; SD, standard deviation.