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. 2021 Jun 10;11:666597. doi: 10.3389/fonc.2021.666597

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Copyright © 2021 Huang, Liang, Lin, Wang, Xie, Lin and Yao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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miR-193b suppresses cervical cancer growth in vivo. Subcutaneous Siha tumors located on mice xenograft models were directly injected with miR-193b for a total of 6 times at 4-day intervals. Tumors were harvested on the 24th day from the injection. (A) miR-193b inhibited cervical cancer growth in vivo. (B) miR-193b expression levels of each group after intratumoral miR-193b injections were measured by qRT-PCR. (C) Effect of miR-193b on tumor growth and tumor volumes. (D) The tumors were weighed after harvested. (E) The protein levels of Ki-67 were detected using IHC. *p < 0.05, **p < 0.01, ***p< 0.001.