TABLE 4.
Comparison of Source Coverage and Overlap of Unique Drug and Drug Labeling Sections.
| Coverage (%) | Overlap (%) | |||||
|---|---|---|---|---|---|---|
| Drug labeling section | Drugs@FDA | DailyMed | DrugBank | Drugs@FDA | DailyMed | DrugBank |
| Boxed warning | 83.01 | 77.79 | — | 36.62 | 39.08 | — |
| Indication | 56.97 | 75.01 | 96.49 | 89.07 | 80.75 | 66.04 |
| Dosage and admin | 67.85 | 88.97 | — | 41.87 | 31.93 | — |
| Use in specific populations | ||||||
| Pregnancy | 74.44 | 85.07 | — | 39.97 | 34.97 | — |
| Lactation | 94.56 | 68.52 | — | 33.35 | 46.03 | — |
| Clinical pharmacology | ||||||
| Mechanism of action | 56.23 | 51.64 | 96.93 | 86.67 | 91.46 | 53.47 |
| Pharmacodynamics | 43.38 | 38.04 | 95.51 | 84.36 | 91.10 | 38.97 |
| Pharmacokinetics | ||||||
| Absorption | 41.48 | 34.33 | 96.68 | 82.69 | 91.26 | 36.63 |
| Food effect | 92.35 | 63.14 | — | 30.04 | 43.94 | — |
| Distribution | 53.05 | 44.09 | 88.28 | 76.87 | 85.33 | 44.28 |
| Metabolism | 47.92 | 38.73 | 96.07 | 81.26 | 90.97 | 42.26 |
| Excretion | 49.43 | 41.36 | 93.97 | 81.10 | 89.30 | 43.29 |
| Drug | 90.12 | 71.00 | 91.28 | 82.00 | 95.96 | 82.89 |
The coverage represents the percentages are relative to total counts of 3,624 unique drug, 977 unique boxed warning section, 3,414 unique indication section, 2,883 unique dosage and administration section, 2,578 unique pregnancy section, 1,655 unique lactation section, 3,356 of mechanism of action section, 3,294 pharmacodynamics section, and 3,134 absorption section, 510 food effect section, 2,722 distribution section, 3,101 metabolism section, 3,051 excretion section parsed from pharmacokinetics section. The overlap represents the percentages of the average number of sources sharing each labeling section.