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. 2021 Jun 10;9:685128. doi: 10.3389/fbioe.2021.685128

TABLE 1.

hAM and ACM used as an implanted membrane.

hAM or ACM Indication No. of patients Graft storage format Graft size (mm)/Side Multilayered use/folding Pre- and post-surgical care Fate/Resorption References and year
hAM Gingival recession 1 Lyophilized or dehydrated Adapted to size of defect No Mouth rinses with Chlorhexidine ND Shetty et al., 2014
Gingival recession 3 Dehydrated and sterilized Adapted to size of defect No Antibiotics No tooth brushing for 3 weeks Mouth rinses with Chlorhexidine for 3 weeks ND Sharma and Yadav, 2015
Gingival recession 15 Lyophilized and irradiated (rq: dehydrated written in title) 10 × 10 mm (?) (rq: written 1 × 1 mm in the article) No Mouth rinses with Chlorhexidine just before surgery and continued after surgery Improvement in width of keratinized gingiva at 3 months and 6 months Jain et al., 2017
Gingival recession 10 Lyophilized and irradiated Adapted to size of gingival recession No Pre-surgical mouth rinses with Chlorhexidine Mouth rinses for 4 weeks No tooth brushing for 4 weeks Suture removal at day 10 ND Rehan et al., 2018
Bone defect in the furcation 5 Lyophilized and gamma-irradiated Adapted to size of defect No Antibiotics for 1 week Mouth rinses with Chlorhexidine twice a day for 4 weeks Suture removal at day 7 ND Kothiwale et al., 2009
Bone defect in the furcation 1 Lyophilized and irradiated Adapted to size of bone defect No Antibiotics Mouth rinses with Chlorhexidine for 1 week ND Kumar et al., 2017
Bone defect in the furcation 15 Dehydrated or lyophilized (?) according to figure 4 in the article Adapted to size of bone defect No Antibiotics for 5 days Mouth rinses with Chlorhexidine 2 times a day for 2 weeks Tooth brushing with a soft toothbrush Suture removal at day 7 ND Kaur and Bathla, 2018
Intrabony defect in interproximal areas 30 Lyophilized and irradiated 30 × 30 mm No Antibiotics for 1 week Suture removal at 1 week ND Kumar et al., 2015
Intrabony defects in interproximal areas 10 Lyophilized and irradiated Adapted to size of defect Bio-Oss bone allograft covered with a double layer of hAM, with excess folded Antibiotics for 1 week Mouth rinses with Chlorhexidine for 4 weeks No tooth brushing for 2 weeks, then only using an extra-soft toothbrush Suture removal at 2 weeks ND Kiany and Moloudi, 2015
Surgical wound after implant surgery 15 Cryopreserved Adapted to size of wound Mesenchymal side in contact with wound No Antibiotics for 1 week Mouth rinses with Chlorhexidine for 2 weeks At 3 and 6 days: Epithelialization obtained faster on the hAM side than on the standard procedure side Velez et al., 2010
BRONJ 2 Cryopreserved 30 × 30 mm No ND ND Ragazzo et al., 2018
ACM Alveolar ridge preservation 20 Deepithelialized and dehydrated (irradiated?) Adapted to size of defect No No antibiotics Epithelialization in 2 weeks approximately Hassan et al., 2017
Alveolar ridge preservation 2 Deepithelialized and dehydrated (irradiated?) 8 × 8 mm No Pre-operative care: mouth rinses with Chlorhexidine for 3 days Antibiotics for 5 days Tooth brushing with tap water After 1 month: mature epithelium Cullum and Lucas, 2019
Alveolar ridge preservation 21 Dehydrated Adapted to size of defect No Prophylactic antibiotics and mouth rinses with Chlorhexidine before surgery Antibiotics for 10 days Mouth rinses with hydrogen peroxide for 2 weeks Epithelialization in 2 weeks Faraj et al., 2020
Peri-implantation wound management 15 Deepithelialized, dehydrated and irradiated Adapted to size of gingiva around implant No Avoid injuries Mouth rinses (not with Chlorhexidine) After 2 weeks: the environment around the implant is covered with keratinized gingiva De Angelis et al., 2019
Intrabony defect in interproximal area 1 Deepithelialized and dehydrated 25 × 15 mm ACM was cut in half: one half was placed on the root surface. FDBA was covered by the other half Double layer of ACM around FDBA, the first layer was folded on the grafted bone before applying the second layer Antibiotics for 1 week Mouth rinses with Chlorhexidine for 2 weeks No tooth brushing for 2 weeks at the site ND Hamada et al., 2020
Schneider membrane perforation repair 9 Deepithelialized and dehydrated (irradiated?) Adapted to size of perforation, 3 mm wider 2 layers with combination of particulate bone allograft and bone xenograft in between Antibiotics for 10 days Nasal decongestants: Oxymetazoline nasal spray for 3 days, Pseudoephedrine for 1 week ND Holtzclaw, 2015

Number of applications = 1. ND: not done; ? = information assumed by the authors according to article content; FDBA: freeze-dried bone allograft.