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The involvement of HDAC5 in epithelial-mesenchymal transition (EMT) processes.
| Tumor Type | Up/down regulated | Target Genes | References |
|---|---|---|---|
| Hepatocellular carcinoma | Up | HIF1α | (70) |
| Up | Tbx3 | (71) | |
| Gastric cancer | Up | MMP9 | (25) |
| Lung cancer | Up | E2F1, E2F3, Twist1 | (27) |
| Up | HK2 | (72) | |
| Up | E2F1, E2F3, Twist1, MMP2, MMP9, Vimentin | (27) | |
| Glioma | Down | E-cadherin, Vimentin | (73) |
| Urothelial Carcinoma | Down | Cytokeratin 5, E-Cadherin, Vimentin | (61) |
