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. 2021 Jun 10;12:683151. doi: 10.3389/fendo.2021.683151

Figure 6.

Figure 6

Regulation of HN on redox system in ACVD. HN activates AMPK and PI3K/AKT, JAK2/STAT3 signaling pathways, induces CMA, promotes Nrf2 release, and inhibits JNK/p38MAPK pathway, inhibits oxidative stress damage and ACVD (inside the box: the red font represents the future research direction, the blue thick arrow represents the influence of HN on the five signal pathways, and other signs form a signal network).