FIGURE 1.

Intraocular pressure was measured using a calibrated applanation tonometer Tonopen XL by Reichert Technologies (the transducer was placed on the same spot of the cornea for each measurement). Intraocular pressure was assessed in normal rats, and values between 13–19 mmHg were considered as normal. Then, the values were assessed before retrobulbar application, and after retrobulbar application of saline (0.1 ml/each eye) (control), BPC 157 1 μg/0.1 ml saline/each eye, or L-NAME 0.5 mg/0.1 ml saline/each eye, at 1, 2, 4, 6, 8, and 10 minutes thereafter. No difference vs. control was noted. 10 rats per experimental group and period for all experiments.