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. 2021 Jun 10;11:670726. doi: 10.3389/fonc.2021.670726

Table 3.

Last results of KEYNOTE 006, CheckMate 066 and CheckMate 067 trial.

KEYNOTE 006 (53) CheckMate 066 (54) CheckMate 067 (55)
Treatment arm Pembrolizumab Nivolumab Nivolumab + ipilimumab
Last update 5 years 5 years 5 years
mPFS 8.4 5.1 11.5
PFS NR 28% 36%
mOS 32.7 37.3 NR (more than 60)
OS 38.7% 39% 52%
ORR 42% 42% 58%
trAEs G3–4 17% 15% 59%