Table 1.
A – Characteristics of the study population and arterial blood gas analysis data at the time of Emergency Room (ER) admission.
n | Tot. | % of n | Mean | DS | ||
---|---|---|---|---|---|---|
Age | 349 | 69,20 | 13,40 | |||
Sex | 349 | |||||
Male | 232 | 66,5% | ||||
Female | 117 | 33,5% | ||||
Smoking | 277 | |||||
Never | 235 | 84,8% | ||||
Former/current | 42 | 15,2% | ||||
Comorbidities | 349 | |||||
Systemic arterial hypertension or Chronic Atrial fibrillation | 239 | 68,5% | ||||
Diabetes mellitus | 69 | 19,8% | ||||
Cerebrovascular accidents and/or ischemic heart disease | 58 | 16,6% | ||||
Chronic obstructive pulmonary disease (COPD) or asthma | 45 | 12,9% | ||||
Chronic kidney failure | 35 | 10,0% | ||||
Active neoplasm (or diagnosis <5 years) | 31 | 8,9% | ||||
Obesity | 29 | 8,3% | ||||
Immunodepression and/or autoimmune disease | 21 | 6,0% | ||||
Venous thromboembolism | 7 | 2,0% | ||||
Obstructive sleep apnea syndrome (OSAS) | 7 | 2,0% | ||||
Interstitial lung disease | 2 | 0,6% | ||||
Miscellaneous | 139 | 39,8% | ||||
≥2 comorbidities | 349 | 172 | 49,3% | |||
Symptoms | 349 | |||||
Fever | 291 | 83,4% | ||||
Dyspnea | 224 | 64,2% | ||||
Cough | 159 | 45,6% | ||||
Dysgeusia/ageusia | 32 | 9,2% | ||||
Anosmia | 39 | 11,2% | ||||
Diarrhea | 52 | 14,1% | ||||
Abdominal pain | 26 | 7,1% | ||||
Headache | 36 | 9,8% | ||||
Fatigue Mental confusion/delirium | 132 29 | 35,9% 8,3% | ||||
ER admission | ||||||
FiO2 | 349 | 0,24 | 0,11 | |||
FiO2 > 0,21 | 349 | 25 | 7,2% | |||
SpO2 | 260 | 91,8 | 5,9 | |||
ABG/PaO2 and P/F available | 308 | 88,3% | ||||
ABG/PaO2, PaCO2 and P/F available | 305 | 87,4% | ||||
pH | 7,47 | 0,05 | ||||
PaO2 (mmHg) | 63,8 | 16,4 | ||||
STPaO2 (mmHg) | 50,6 | 18,5 | ||||
PaCO2 (mmHg) | 32,1 | 5,0 | ||||
HCO3- standard (mmol/L) | 24,0 | 3,2 | ||||
PF | 286,7 | 79,3 | ||||
STP/F | 225,8 | 80,5 | ||||
PF<200 | 308 | 31 | 10,1% | |||
STP/F <200 | 305 | 117 | 38,4% | |||
Days from symptoms start to ER admission | 6,1 | 2,0 | ||||
Days from symptoms start to Pulmonology Unit admission | 9,6 | 7,7 | ||||
Days from ER admission to Pulmonology Unit admission | 3,5 | 5,7 | ||||
Table 1. B – Arterial blood gas analysis data at the time of Pulmonology Unit admission and outcomes of the study population. |
n | Tot. | % of n | Mean | DS | ||
---|---|---|---|---|---|---|
Pulmonology Unit admission | ||||||
Previous hospital setting | 349 | |||||
ER | 201 | 57,6% | ||||
General Medicine Units | 70 | 20,1% | ||||
Infectious diseases Unit | 44 | 12,6% | ||||
Other units | 34 | 9,7% | ||||
Respiratory treatment/support applied | 349 | |||||
Standard oxygen therapy | 202 | 57,8% | ||||
High flow nasal oxygen | 106 | 30,4% | ||||
Continuous positive airway pressure | 31 | 8,9% | ||||
Non invasive ventilation | 7 | 2,0% | ||||
Thoracic high Resolution Computed Tomography/ pattern | 333 | |||||
Ground glass opacities | 146 | 43,8% | ||||
Consolidation ± Ground glass opacities | 187 | 56,2% | ||||
FC (bpm) | 337 | 80,1 | 13,4 | |||
FR (breaths/minute) | 322 | 22,3 | 5,4 | |||
FiO2 | 349 | 0,51 | 0,20 | |||
SpO2 (%) | 344 | 95,8 | 2,7 | |||
ABG available | 349 | |||||
ph | 7,44 | 0,40 | ||||
PaO2 (mmHg) | 85,7 | 25,4 | ||||
STPaO2 (mmHg) | 78,3 | 26,8 | ||||
PaCO2 (mmHg) | 35,5 | 5,0 | ||||
PaCO2 ≤ 40 mmhg | 309 | 88,5% | ||||
HCO3 (mmol/L) | 25,6 | 3,4 | ||||
P/F | 349 | 189,4 | 61,9 | |||
STP/F | 349 | 172,4 | 80,1 | |||
P/F<200 | 349 | 196 | 56,2% | |||
STP/F <200 | 349 | 249 | 71,3% | |||
Outcomes | ||||||
Outcome failure | 349 | 113 | 32,4% | |||
Deaths | 349 | 58 | 16,6% | |||
Need for Invasive mechanical ventilation (IMV) | 349 | 77 | 22,1% | |||
Need for respiratory treatment step up Survival, from symptoms start to date of death (days) Survival, from ER admission to date of death (days) | 349 58 58 | 172 | 49,3% | 21,0 16,8 | 13.4 13,3 | |
Days from ER Admission to recovery from ARF | 291 | 21,6 | 9,9 |