FIGURE 2.

SARS-CoV-2-specific IFN-γ-producing T cell responses reactive to the S glycoprotein (red), the N protein (green), and the M protein (blue) (A) and proportion of patients with positive (>25 S-reactive, >14 N-reactive and >21 M-reactive SFUs/10⁶ PBMCs) responses (B) by the IFN-γ FluoroSpot assay according to the interval from the diagnosis of COVID-19 to the assessment. Horizontal bars and whiskers represent median values and interquartile ranges, respectively. Comparisons were performed with the Mann-Whitney U test. IFN-γ, interferon-γ; PBMC, peripheral blood mononuclear cell; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; SFU, spot forming unit