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. 2021 Jun 29;60(31):17102–17107. doi: 10.1002/anie.202104453

Figure 2.

Figure 2

AFM, TEM, synchrotron FTIR and Raman characterization of SARS‐CoV‐2 virus. A–E) A) TEM image of SARS‐CoV‐2 sample with single virion marked by black square. B) Magnification of the area marked by the black square in (A), showing a single SARS‐CoV‐2 particle with its characteristic morphological appearance. C) AFM height and D) AFM deflection images of SARS‐CoV‐2 sample, demonstrating multiple round structures. E) Synchrotron FTIR spectrum and its 2nd derivative transform with the most prominent bands marked. The bands are color‐coded as follows: lipids (blue), proteins (green) and nucleic acids (orange). F) Raman spectrum (532 nm) of SARS‐CoV‐2 virions (red) compared to spectrum of purified RNA (black) with labelled bands.