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. 2021 Jun 22;218(8):e20202446. doi: 10.1084/jem.20202446

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© 2021 Xu et al.

This article is available under a Creative Commons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).

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Figure 6. — GKO rescues novel object recognition behavior in the J20 mouse model. (A) Diagram representing the novel object recognition test. (B) Memory behavior in 6-mo-old J20;WT mice (five males and three females) and J20;GSAP KO mice (J20;KO; four males and six females) were evaluated by novel object recognition test. Left: Total distance traveled during the rehabituation phase was quantified. Middle: Exploration times for old and novel objects during the choice phase were quantified in both genotypes. Right: Preference index = (time novel − time familiar)/(time novel + time familiar). Data represent mean ± SEM; unpaired t test; *, P < 0.05; N.S., not significant.