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. 2021 Jun 10;12:667065. doi: 10.3389/fphys.2021.667065

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Copyright © 2021 Ronzhina, Stracina, Lacinova, Ondacova, Pavlovicova, Marsanova, Smisek, Janousek, Fialova, Kolarova, Novakova and Provaznik.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Distributions of selected electrogram parameters (left) and corresponding corrected values Δ calculated by subtracting end-washout value from the current one (right). Shown for stained (n = 9) and non-stained (n = 11) hearts. QRS_D, RR_D, QT_D, QRS_A, and T_A, duration of QRS complex, RR and QT intervals and maximal absolute QRS deviation and maximal deviation of ST-T interval, respectively. Displayed for end-washout (WT, according to the notation used in experimental protocol with di-4-ANEPPS) minute and every minute of ischemia and reperfusion as median; the edges of the box indicate 25th–75th percentiles. Horizontal lines indicate significant difference (p < 0.05) revealed via paired (not calculated for Δ values) and unpaired tests. “+” indicates outlier.