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. 2021 Jun 10;11:680732. doi: 10.3389/fcimb.2021.680732

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Copyright © 2021 Fourie, Albertyn, Sebolai, Gcilitshana and Pohl

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of SET3 deletion on Candida albicans monomicrobial biofilms. Monomicrobial biofilm biomass after 6 h (A) and 48 h (B) of the homozygous mutant of SET3 (set3Δ/Δ) as well as the homozygous mutant with add-back of the wild-type gene (set3Δ/Δ::SET3). Colony forming units (CFU) of mature C. albicans biofilms are indicated in (C) as well as biofilm morphology of mature biofilms in (D) (SC5314), (E) (set3Δ/Δ) and (F) (set3Δ/Δ::SET3). Small panels on right corners indicate biofilms with lower magnification. Scale bars on all panels indicate 10 μm. *Significantly different from wild type (SC5314) (****P < 0.0001).