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Evaluation of angelicin toxicity in bone marrow macrophages (BMMs). (A) Chemical structure of angelicin. (B, C) Effect of angelicin on the cell viability of BMM. The cytotoxic effects of angelicin were detected at the different concentrations for 24 and 48 h using CCK-8 assay. (D, E) Representative image of apoptosis rate detected by flow cytometry of each group. The values presented are the mean ± SD of five independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001 (ANOVA).
