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. 2021 Jun 15;24(2):583. doi: 10.3892/mmr.2021.12222

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Copyright: © Zheng et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Circulating microRNAs (miRs) may serve as biomarkers in human body fluids for various types of cancer. Liquid biopsy is a less invasive method that may detect cancer biomarkers more frequently and efficiently than other methods and is a good candidate method for future use in cancer diagnosis. miRs, microRNAs; VEGF, vascular endothelial growth factor; VEGFR, VEGF receptor; RGS3, regulator of G protein signaling 3; PKD1, polycystin 1; LPIN1, lipin 1; TGF-β, transforming growth factor-β; TGF-βR1, TGF-β receptor 1; COL18A1, collagen type XVIII alpha 1 chain; THB2, truncated hemoglobin 2; THBS1, thrombospondin 1; PTCH1, patched 1; PHD3, prolyl hydroxylase 3; PTEN, phosphatase and tensin homolog; FOXO1, forkhead box O1; NF-κB, nuclear factor κ-B.