Table 4. Association Between Adolescent OSA and Orthostatic BP Reactivity.
| Variable | Model 1a | Model 2a | Model 3a | |||
|---|---|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | |
| Hyporeactivity | ||||||
| AHI <2 | 1 [Reference] | NA | 1 [Reference] | NA | 1 [Reference] | NA |
| AHI 2 to <5 | 1.1 (0.5-2.2) | .81 | 1.0 (0.5-2.2) | .96 | 1.0 (0.5-2.0) | .92 |
| AHI ≥5 | 1.6 (0.6-4.2) | .34 | 1.5 (0.5-4.3) | .45 | 1.3 (0.5-3.8) | .61 |
| Hyperreactivity | ||||||
| AHI <2 | 1 [Reference] | NA | 1 [Reference] | NA | 1 [Reference] | NA |
| AHI 2 to <5 | 1.3 (0.6-2.7) | .44 | 1.3 (0.6-3.0) | .46 | 1.5 (0.7-3.2) | .32 |
| AHI ≥5 | 3.3 (1.4-7.5) | .006 | 3.1 (1.2-8.5) | .02 | 3.9 (1.5-10.2) | .005 |
Abbreviations: AHI, apnea-hypopnea index; BP, blood pressure; NA, not applicable; OSA, obstructive sleep apnea; VAT, visceral adipose tissue.
a
Model 1 = univariate association of AHI with orthostatic BP reactivity. Model 2 = multivariable association of AHI with orthostatic BP reactivity after adjusting for sex, race/ethnicity, age, tonsillar hypertrophy, adenotonsillectomy, antihypertensive and cardiac medication use, and VAT (z score). Model 3 = multivariable association of AHI with orthostatic BP reactivity after adjusting for sex, race/ethnicity, age, tonsillar hypertrophy, adenotonsillectomy, antihypertensive and cardiac medication use, and metabolic syndrome risk score (z score).