Table 1:
Pre-Transplant Characteristics of Study Population Prior to Propensity Matching
| Variable |
All Patients (n=14357) |
Bridge to Transplant (n=5359) |
Medical Management (n=8998) |
p-value |
|---|---|---|---|---|
| Age (years), median (IQR) | 56 (47 – 63) | 56 (47 – 63) | 56 (47 – 63) | 0.523 |
| Male Gender, n(%) | 10556 (73.4) | 4306 (80.4) | 6250 (69.5) | <0.001 |
| Ethnicity | <0.001 | |||
| White | 9730 (67.8) | 3586 (66.9) | 6144 (68.3) | |
| African American | 2901 (20.2) | 1223 (22.8) | 1678 (18.7) | |
| Hispanic | 1097 (7.6) | 349 (6.5) | 748 (8.3) | |
| Other | 629 (4.4) | 201 (3.8) | 428 (4.8) | |
| Diabetes, n(%) | 3939 (27.5) | 1641 (30.7) | 2298 (25.6) | <0.001 |
| CVA, n(%) | 768 (5.4) | 300 (5.6) | 468 (5.2) | 0.293 |
| Smoking, n(%) | 6803 (47.5) | 2860 (53.5) | 3943 (44.0) | <0.001 |
| AICD, n(%) | 11350 (79.5) | 4287 (80.5) | 7063 (79.0) | 0.024 |
| Blood Type O, n(%) | 5500 (38.3) | 2422 (45.2) | 3078 (34.2) | <0.001 |
| BMI (mg/kg2) | 27.1 ± 4.8 | 28.1 ± 4.9 | 26.5 ± 4.7 | <0.001 |
| Non-Dilated Myopathy, n(%) | 1510 (10.5) | 107 (2.0) | 1403 (15.6) | <0.001 |
| Status @ Listing | <0.001 | |||
| Status 1A | 3212 (22.8) | 1493 (28.9) | 1719 (19.3) | |
| Status 1B | 6389 (45.4) | 2675 (51.8) | 3714 (41.7) | |
| Status 2 | 4461 (31.7) | 992 (19.2) | 3469 (40.0) | |
| Status 1A @ Transplant | 8230 (57.3) | 3820 (71.3) | 4410 (49.0) | <0.001 |
| Functional Status | <0.001 | |||
| Poor | 4041 (28.8) | 1451 (27.7) | 2563 (29.4) | |
| Moderate | 7747 (55.5) | 2871 (54.7) | 4876 (56.0) | |
| Excellent | 2196 (15.7) | 926 (17.6) | 1270 (14.6) | |
| eGFR (mL/min/1.73m2) | 72.5 ± 33.6 | 73.8 ± 29.9 | 71.7 ± 35.6 | <0.001 |
| Days on WL, median(IQR) | 98 (29 – 264) | 191 (77 – 404) | 60 (20 – 176) | <0.001 |
| Mean PA Pressures (mmHg) | 27.7 ± 10.1 | 26.3 ± 10.1 | 28.6 ± 10.0 | <0.001 |
| PVR (Woods Units) | 2.46 ± 1.75 | 2.29 ± 1.72 | 2.57 ± 1.76 | <0.001 |
CVA, cerebrovascular accident; AICD, automated internal cardioverter defibrillator; BMI, body mass index; eGFR, estimated glomerular filtration rate; WL, waiting list; PA, pulmonary artery; PVR, pulmonary vascular resistance; IQR, interquartile range