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. Author manuscript; available in PMC: 2021 Jun 24.
Published in final edited form as: Circulation. 2019 Jun 17;140(6):459–469. doi: 10.1161/CIRCULATIONAHA.118.036932

Table 2:

Variables Associated With LVAD Support at time of Transplant

Variable OR (95% CI) p-value OR (95% CI) p-value

Univariable Analysis Multivariable Analysis
Age (Years) 1.00 (1.00 – 1.00) 0.557
Male Gender, n(%) 1.80 (1.66 – 1.95) <0.001 1.42 (1.27 – 1.58) <0.001
Ethnicity <0.001 <0.001
White (Reference) (Reference)
African American 1.25 (1.15 – 1.36) 1.21 (1.08- 1.36)
Hispanic 0.80 (0.70 – 0.91) 0.85 (0.70 – 1.02)
Other 0.80 (0.68 – 0.96) 0.97 (0.77 – 1.23)
Diabetes, n(%) 1.29 (1.19 – 1.39) <0.001 1.06 (0.96 – 1.18) 0.184
CVA, n(%) 1.08 (0.93 – 1.26) 0.293
Smoking, n(%) 1.46 (1.37 – 1.57) <0.001 1.26 (1.15 – 1.38) <0.001
AICD, n(%) 1.10 (1.01 – 1.20) 0.025 0.87 (0.76 – 0.98) 0.070
Blood Type O, n(%) 1.59 (1.48 – 1.70) <0.001 1.28 (1.16 – 1.40) <0.001
BMI (kg/m2) 1.08 (1.07 – 1.09) <0.001 1.05 (1.04 – 1.06) <0.001
Non-Dilated Myopathy 0.11 (0.09 – 0.13) <0.001 0.12 (0.09 – 0.15) <0.001
Status @ Listing <0.001 <0.001
Status 1A (Reference) (Reference)
Status 1B 0.83 (0.76 – 0.90) 0.71 (0.63 – 0.80)
Status 2 0.87 (0.81 – 0.93) 0.16 (0.14 – 0.19)
Status 1A @ Transplant 2.58 (2.40 – 2.78) <0.001 2.94 (2.65 – 3.26) <0.001
Functional Status <0.001 <0.001
Poor (Reference) (Reference)
Moderate 1.04 (0.96 – 1.13) 1.69 (1.51 – 1.89)
Excellent 1.29 (1.16 – 1.43) 2.29 (1.98 – 2.66)
eGFR (mL/min/1.73m2) 1.00 (1.00 – 1.00) <0.001 1.01 (1.00 – 1.01) <0.001
PVR (Woods Units) 0.89 (0.87 – 0.91) <0.001 0.93 (0.91 – 0.96) <0.001
Wait List Time > 6mo. 3.33 (3.10 – 3.58) <0.001 5.90 (5.28 – 6.59) <0.001
UNOS Region <0.001 <0.001
 1 (Reference) (Reference)
 2 0.61 (0.50 – 0.74) 0.63 (0.49 – 0.82)
 3 0.38 (0.31 – 0.47) 0.33 (0.25 – 0.43)
 4 0.51 (0.42 – 0.62) 0.57 (0.44 – 0.75)
 5 0.40 (0.33 – 0.49) 0.57 (0.44 – 0.74)
 6 1.75 (1.35 – 2.27) 3.28 (2.33 – 4.61)
 7 1.20 (0.98 – 1.47) 1.35 (1.03 – 1.76)
 8 0.69 (0.56 – 0.85) 0.88 (0.66 – 1.16)
 9 1.11 (0.90 – 1.37) 0.92 (0.70 – 1.22)
 10 1.06 (0.87 – 1.30) 1.21 (0.93 – 1.58)
 11 0.79 (0.65 – 0.96) 0.86 (0.67 – 1.12)

CVA, cerebrovascular accident; AICD, automated internal cardioverter defibrillator; BMI, body mass index; eGFR, estimated glomerular filtration rate; WL, waiting list; PA, pulmonary artery; PVR, pulmonary vascular resistance; UNOS, United Network of Organ Sharing