TABLE 4.

CPN-CD Has Superior Discrimination Compared With the Hepatic Steatosis Index

		CPN-CD		HSI Index (Native)		HSI (Recalibrated)		HSI (Revised)
C-statistic (95% CI)		0.848 (0.804–0.892)		0.763 (0.708–0.819)		0.763 (0.709–0.819)		0.779 (0.725–0.833)
Net Reclassification Index	RI for NAFLD	Ref	Ref	–0.30	+0.08	–0.20	–0.28	–0.13	–0.19
	RI for normal		Ref		–0.38		+0.08		+0.06
	P		Ref		<0.001		<0.001		<0.001

The C-statistic represents the area under the receiver operating curve (plotting the sensitivity by the 1-specifcity). The Net Reclassification Index is the sum of the proportion of patients with NAFLD who are reclassified correctly and the proportion of patients with a normal liver who are reclassified correctly. The NRI P value refers to the results of the McNemar test.

Abbreviations: CI, confidence interval; RI, reclassification improvement.