Table 3. In vitro Drug Release Data of the Formulated Batches.
zero
order |
first
order |
Higuchi
model |
Hixson
Crowell model |
Korsmeyer–Peppas model |
|||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Batches | r2 | k0 | r2 | k1 | r2 | kH | r2 | kHC | r2 | Kkp | n |
core tablet | 0.293 | 0.111 | 0.993 | –0.020 | 0.566 | 3.615 | 0.957 | –0.047 | 0.695 | 1.828 | 0.070 |
F1GG | 0.394 | 0.128 | 0.962 | –0.010 | 0.678 | 3.915 | 0.888 | –0.022 | 0.862 | 1.688 | 0.126 |
F2GG | 0.505 | 0.143 | 0.948 | –0.006 | 0.779 | 4.155 | 0.889 | –0.014 | 0.935 | 1.540 | 0.182 |
F3GG | 0.604 | 0.152 | 0.850 | –0.003 | 0.851 | 4.211 | 0.884 | –0.009 | 0.975 | 1.449 | 0.211 |
F4GG | 0.671 | 0.153 | 0.940 | –0.003 | 0.894 | 4.138 | 0.890 | –0.006 | 0.994 | 1.359 | 0.238 |
F1TGG | 0.474 | 0.078 | 0.960 | –0.004 | 0.719 | 2.891 | 0.884 | –0.010 | 0.922 | 1.569 | 0.159 |
F2TGG | 0.595 | 0.090 | 0.969 | –0.003 | 0.824 | 3.158 | 0.896 | –0.007 | 0.957 | 1.398 | 0.220 |
F3TGG | 0.688 | 0.096 | 0.968 | –0.002 | 0.890 | 3.268 | 0.903 | –0.005 | 0.986 | 1.292 | 0.254 |
F4TGG | 0.816 | 0.101 | 0.958 | –0.001 | 0.960 | 3.275 | 0.911 | –0.003 | 0.994 | 1.076 | 0.318 |