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. Author manuscript; available in PMC: 2022 Jun 1.
Published in final edited form as: J Allergy Clin Immunol. 2021 Mar 10;147(6):2271–2280.e8. doi: 10.1016/j.jaci.2021.02.038

Table 1:

Study population baseline characteristics.

Subject Age Gender Duration IgE Dosing BslUAS7 MidPtDay BasoPheno BasoCount
1 62 F 5 191 0.019 24.5 20 NR B
2 34 F <1 347 0.013 16.5 10 R NB
3 50 F 4 133 0.024 23.5 20 NR B
4 32 F <1 21.4 0.238 32 6 R NB
5 62 F 4 78.6 0.027 22 10 R NB
6 39 F <1 5.3 0.821 32 10 NR B
7 31 M 2 610 0.004 20.5 6 R NB
8 33 F 16 1558 0.002 25.5 20 R B
9 39 M 1 < 2 2.054 42 30* NR B
10 52 M 50 153 0.020 30.5 30* Unclassified B
11 35 M <1 < 2 1.586 35.5 20 NR B
12 54 M 1 13.5 0.289 36 30* NR B
13 67 F 10 70.8 0.059 29 6 NR NB
14 36 F 20 146 0.025 21.5 6 R NB
15 71 F 2 149 0.037 41.5 30 NR NB
16 29 M 8 4.2 0.854 32 30* NR B
17 36 F 1 197 0.016 34 6 NR NB
18 22 F 6 56.3 0.084 23.5 30 R NB
Average 44 67% F 7.4 207 0.340 29 17.7
R/NB 36 83% F 5.6 210 0.065 23^ 11.3
NR/NB 58 100% F 4.3 139 0.037 35 14.0
NR/B 44 43% F 2.9 50 0.807 32 22.9
*

Indicates subjects that did not reach 50% UAS-7 reduction by day 30.

^

ANOVA p=0.0473

Duration = years of disease

Dosing = calculated dose of omalizumab in mg, per Kg body weight per IU IgE

BslUAS-7 = baseline UAS-7 score

MidPtDay = day at which symptom drop was greater than 50%

BasoPheno = anti-IgE functional category for the subject (NR = non-responder, R = responder)

BasoCount = Basophil count (B = basopenic, NB = non-basopenic)