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. 2021 Jun 10;8:682367. doi: 10.3389/fmolb.2021.682367

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Copyright © 2021 Zhao and He.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The promotive effect of LPC on the activation of the PKC signaling in EPCs. (A,B) The mRNA expression of PKC-β1 and TGF- β1 after LPC or PC treatment in EPCs were measured by RT-qPCR. (C,D) The protein levels of p-PKC and TGF-β1 were in EPCs treated with LPC or PC were accessed using western blot. (E) Immunofluorescence staining was used to determine the location of PKC-β1 after the LPC or PC treatment in EPCs (Figure 5D). **p < 0.01, ***p < 0.001 compared with the control, ^# p < 0.05, ^## p < 0.01 compared with the LPC group.