Table 1. Summary of confirmed O. lupi infections reported in humans.
Case | Age (years)/Sex of patient | Geographical location | Year | Anatomical location of the lesion | Parasite sex | Diagnosis | Method of confirmation | Treatment | Reference |
1 | 8/NR | Tunisia | 2005† | Right eye | NGF | Ophthalmoscopy | Morphology | Surgical excision | [38] |
2 | 18/F | Turkey | 2011 | Left eye | NGF | Biomicroscopy + Imaging | Morphology + Molecular | Surgical excision | [29] |
3 | 26/M | Turkey | 2012 | Right eye | NGF | Ophthalmoscopy | Morphology + Molecular | Surgical excision | [38] |
4 | 2/F | Arizona, USA | 2013 | Upper cervical spinal cord | GF | Imaging | Morphology | Surgical excision, albendazole, ivermectin | [15] |
5 | 20/M | Qom, Iran | 2013 | Left eye | NGF | Biomicroscopy + Imaging | Morphology + Molecular | Surgical excision | [17] |
6 | 28/M | Turkey | 2013 | Right eye | NGF | Biomicroscopy | Morphology + Molecular | Surgical excision | [16] |
7 | 10/F | New Mexico, USA | 2013 | Right posterior-parietal scalp | NGF | Macroscopic observation | Morphology + Molecular | Surgical excision | [52] |
8 | 50/F | Arizona, USA** | 2014 | Subcutaneous forearm | NGF | Imaging | Morphology + Molecular | Surgical excision, doxycycline, ivermectin | [52] |
9 | 28/M | Erlangen, Germany* | 2014 | Right eye | NR | Ophthalmoscopy | Molecular | Surgical excision | [18] |
10 | 5/F | New Mexico, USA | 2014 | Upper cervical spinal cord | GF | Imaging | Morphology | Surgical excision, doxycycline, ivermectin | [9] |
11 | 10/M | Texas, USA | 2014 | Left eye | NGF | Imaging | Morphology + Molecular | Surgical excision, doxycycline, ivermectin | [52] |
12 | 13/M | Arizona, USA | 2015 | Upper cervical spinal cord | NGF | Imaging | Morphology | Surgical excision, doxycycline, ivermectin | [8] |
GF: gravid female, NGF: Nongravid female, NR: not reported, *: travel history to Tunisia and Turkey, **: travel history to Jamaica and Utah, USA, †Redescribed in 2012.