Table 1.

OR with 95% CI of developing MS among subjects categorised by DRB1*15:01 status, compared with DRB1*15:01 negative subjects

DRB1*15:01	ca/co*	OR (95% CI)†	OR (95% CI)‡
0	3093/4830	1.0 (reference)	1.0 (reference)
1	3406/1719	3.1 (2.9 to 3.3)	3.7 (3.3 to 4.1)
2	732/183	6.2 (5.2 to 7.4)	7.8 (6.4 to 9.5)

*Number of exposed cases and controls.

†Adjusted for study, age, sex, residential area and ancestry.

‡Adjusted for study, age, sex, residential area, ancestry, smoking, anti-EBNA-1 status, adolescent BMI, rs9277565, rs2229092, DRB1*03:01, DRB1*13:03, DRB1*08:01, A*02:01, B*44:02, B*38:01, B*55:01, DQA1*01:01, DQB1*03:02 and DQB1*03:01. Homozygote correction was made for DRB1*03:01 and A*02:01.

BMI, body mass index; MS, multiple sclerosis.