Table 1.
NOTCH3 variant carriers | Non-NOTCH3 variant carriers | P value | |
Number of cases | 443 | 200 189 | |
Mean (SD) age at recruitment (years) | 55.7 (8.2), range 40–70 | 56.5 (8.2) range 38–72 | 0.06 |
Male sex (%) | 223 (50) | 89 872 (45) | 0.02 |
White ethnic background (%) | 378 (85) | 187 912 (94) | 1.53×10–15 |
Mean (SD) BMI (kg/m2) | 27.8 (5.0) | 27.4 (4.8) | 0.12 |
Non-smoker (%) | 399 (90.0) | 180 955 (90.4) | 0.82 |
Blood pressure medication (%) | 37 (8.4) | 20 171 (10.1) | 0.23 |
Hypertension (%) | 142 (32.1) | 65 361 (32.6) | 0.79 |
Hypercholesterolaemia (%) | 49 (11.1) | 19 085 (9.5) | 0.27 |
Diabetes mellitus (%) | 41 (9.3) | 14 257 (7.1) | 0.08 |
The p values for categorical and continuous variables were calculated by the Pearson’s Χ2 test and two-sample t-test, respectively.
BMI, body mass index.