Figure 5.

Decreased activation of alternative and terminal complement pathway and stabilized renal function after immunosuppression. (A) eGFR decreased slightly among patients who did not receive immunosuppression (P = 0.028). (B) No change in eGFR among patients received immunosuppression. (C) UPCR tended to decrease slightly among patients who did not receive immunosuppression (P = 0.051). (D) UPCR decreased significantly in patients who received immunosuppression (P < 0.0001). (E) Plasma Gd-IgA₁ level tended to decrease 1 months after immunosuppression (N = 17, P = 0.0638) and 3~6 months after immunosuppression (N = 20, P = 0.0019). (F) Plasma C5a significantly decreased 1 (N = 17, P < 0.0001) and 3~6 months after immunosuppression (N = 20, P < 0.0001). (G) Plasma factor Ba level significantly decreased 1 (N = 17, P = 0.0008) and 3~6 months after immunosuppression (N = 20, P = 0.0004). UPCR, urinary protein to creatinine ratio; eGFR, estimated glomerular filtration rate.