Table 2.
Comparisons of baseline characteristics among IgAN patients with and without immunosuppression.
| without immunosuppression (N = 48) | with immunosuppression (N = 27) | ||
|---|---|---|---|
| Age (years) | 41.82 ± 12.40 | 45.75 ± 14.98 | P = 0.3600 |
| Male (%) | 26 (54.17%) | 10 (37.04%) | P = 0.6381 |
| Diabetes (%) | 1 (2.08%) | 2 (7.41%) | P = 0.2462 |
| Hypertension (%) | 24 (50.00%) | 11 (40.74%) | P = 0.4783 |
| Use of ACEi/ARB (%) | 32 (66.67%) | 19 (70.37%) | P = 0.2637 |
| UPCR (g/g) | 1.39 ± 1.30 | 3.78 ± 4.21 | P < 0.0001 |
| Creatinine (mg/dL) | 1.65 ± 1.50 | 1.60 ± 0.98 | P = 0.1190 |
| eGFR (ml/min/1.73m2) | 64.49 ± 37.37 | 48.87 ± 31.70 | P = 0.0609 |
| Gd-IgA1 Ab titer (ng/mL) | 7120 (3847-12163) |
8512 (5228-13802) |
P = 0.2971 |
| C5a (ng/mL) | 2348 (567-4904) |
4350 (2254-5222) |
P = 0.0683 |
| Factor Ba (ng/mL) | 2222 (990-3622) |
3600 (1968-4960) |
P = 0.0032 |
Normally-distributed continuous variables including age, UPCR, creatine, eGFR were expressed as mean ± standard deviation. Non-normally-distributed continuous variables including Gd-IgA1 Ab titer, C5a and Factor Ba level were expressed as median (interquartile range). UPCR, urinary protein to creatinine ratio; eGFR, estimated glomerular filtration rate; ACEi/ARB, angiotensin converting enzyme inhibitor/angiotensin II receptor blocker.