Table 3.
The effects of vitamin A supplement, vitamin A status and retinoic acid treatment on the stearoyl-CoA desaturase 1 activity, mRNA and protein levels in cells and tissues
Treatments
|
Tissue/cells
|
Activity
|
mRNA
|
Protein levels
|
Ref.
|
Vitamin A supplement | Mouse liver | ND | No change | ND | Weiss et al[69] |
Mouse liver | ND | Increased | ND | Miller et al[70] | |
Vitamin A restriction | Muscle tissues of the Japanese Black steers | ND | No change | ND | Hayashi et al[66] |
Vitamin A deficiency | Rat liver | ND | Reduced | No change | Raja Gopal Reddy et al[68] |
Rat kidney | ND | No change | No change | Gopal Reddy et al[71] | |
Rat pancreas | ND | ND | Reduced | Raja Gopal Reddy et al[72] | |
Rat liver microsomal | Increased | ND | ND | Alam et al[74] | |
RA treatments | 3T3-L1 cells | ND | ND | Reduced | Stone and Bernlohr[77] |
Human retinal cells | ND | Induced | ND | Samuel et al[78] |
ND: Not determined; RA: Retinoic acid.