TABLE 2.

30-day In-patient Mortality After Major CRC Resection Immediately Before and During the COVID-19 Pandemic Period

Elective Surgery
	Before Pandemic			During Pandemic			During Versus Before PandemicN = 10,823 patients with complete data on age, sex, stage IV cancer, comorbidities, and socioeconomic deprivation
	N	%	95% CI	N	%	95% CI	Crude Odds Ratio	Adjusted Odds Ratio	95% CI	P	P Interaction
All sites	8774	0.9	0.7–1.2	2267	1.2	0.8–1.8	1.35	1.54	0.98–2.43	0.063
Hot sites	7221	1.0	0.8–1.2	1411	1.4	0.9–2.2	1.47	1.65	0.97–2.82	0.067	0.855
Cold sites	1553	0.7	0.4–1.3	856	0.9	0.4–1.8	1.29	1.49	0.57–3.88	0.413
Emergency Surgery
	Before Pandemic			During Pandemic			During Versus Before Pandemic N = 1994 patients with complete data on age, sex, stage IV cancer, comorbidities, and socioeconomic deprivation
	N	%	95% CI	N	%	95% CI	Crude Odds Ratio	Adjusted Odds Ratio	95% CI	P	P Interaction
All sites	1493	5.6	4.5–6.9	526	8.9	6.6–11.7	1.67	1.74	1.21–2.50	0.003
Hot sites	1232	5.6	4.4–7.0	444	8.8	6.3–11.8	1.65	1.67	1.10–2.52	0.015	0.554
Cold sites	261	5.7	3.3–9.3	82	9.8	4.3–18.3	1.76	2.19	1.02–4.71	0.045

CI, confidence intervals; CRC, colorectal cancer.