TABLE 1.

Deletions at the nucleotide and amino acid levels in L and P proteins

Deletion positions	No. of deleted nucleotides	preS domain of L protein		Spacer of P protein		Reference(s)
		Deletion positions	Substitution	Deletion positions	Substitution
Naturally occurring
2890–2976	87	15–43		196–224	E195G	39
2910–3092	183	22–82		202–262		38
2996–2	222	50–123	S124A	231–304		38
3004–3183	180	53–112		234–283	A233Q	45
3016–3144	129	57–99		238–280		41, 57
3020–3202	183	58–118		239–299		37, 38, 42–44, 51
3026–3208	183	60–120	Q121E	241–301	S240R	38
3031–3141	111	62–98		243–279	I242T	37
3033–3131	99	63–95		243–275		38
3123–3164	42	93–106		273–286		39
Artificial
3004–3174	171	53–109		234–290
3049–3174	126	68–109		249–290	H248P
3091–3174	84	82–109		263–290
3133–3174	42	96–109		277–290	L276P