. 2021 May 21;11(6):332. doi: 10.3390/metabo11060332

Table 3.

AKR1B10 expression in extra-hepatic cancers and its prognostic impact.

Organ	Cancer Type *	Assay	AKR1B10 Level **		Prognosis	References
Organ	Cancer Type *	Assay	Lesion	Serum	Prognosis	References
Colorectum	CRC, ADC	mRNA, protein	Low		Poor	[68,70,71,72,73,74,75,76]
Colorectum	CRC, ADC	mRNA		Low	Poor	[24]
Stomach	ADC	mRNA, protein	Low		Poor	[69,77,78,79]
Lung	NSCLC, SCC, ADC	mRNA, protein	High		Poor	[8,81,82,83,84,85,86,87,88,89,90]
Lung	NSCLC, SCC, ADC	protein		High		[90]
Breast	ADC, ductal carcinoma	mRNA, protein	High		Poor	[91,92,93,94,95,96]
Breast	ADC, ductal carcinoma	protein		High	Poor	[91]
Pancreas	ADC, MCT	protein	High			[55,97]
Oral cavity	SCC	protein	High		Poor	[98,99]

Note: * Abbreviations: ADC, adenocarcinoma; NSCLC, non-small cell lung carcinoma; SCC, squamous cell carcinoma; MCT, mucinous cystic tumor. ** Levels of cancerous lesions and sera of cancer patients compared to those of noncancerous lesions and sera of healthy doners.