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. 2021 May 21;11(6):926. doi: 10.3390/diagnostics11060926

Table 2.

Summary of the different output parameters obtained by the different MRI techniques discussed in this article.

Technique Frequently Used Sequence Output Parameters Contrast Agent Main Disadvantages
DCE T1-weighted
GE EPI
IAUGC
Ktrans
νe
kep
exogenous AIF

Ktrans combined measure
DSC T2-weighted SE
or
T2*-weighted GE
EPI
CBF
CBV
MTT
(Ktrans, νe, kep)
exogenous AIF

first pass measurement
ASL 2D EPI
or
3D GRASE
CBF
Bolus arrival time
Arterial CBV
endogenous low SNR
IVIM PGSE EPI D
D*
fIVIM
endogenous long acquisition time

different approaches
VASO T1-weighted
GE, SE or GRASE EPI
CBV exogenous/endogenous low SNR

only measurement of CBV
iVASO arterial CBV exogenous
SSC T2 -weighted SE
or
T2*-weighted GE
EPI
relative CBV exogenous only measurement of CBV

lack of clinically approved contrast agents
Vessels size imaging SAGE EPI VSI exogenous first pass measurement
or
lack of clinically approved contrast agents
SAGE-based DSC SAGE EPI CBF, CBV, MTT
Ktrans, νe, kep
VSI
exogenous AIF

first pass measurement
2D PC MRA T2-weighted GE total CBF
(CMRO2)
endogenous only measurement of global CBF

choice of optimal VENC
QSM 3D multi-echo GE OEF
(CMRO2)
endogenous assumes isotropic magnetic susceptibilities

relative quantification
qBOLD (multi echo)
GE/SE EPI
or
asymmetric SE EPI
DBV
OEF
(CMRO2)
endogenous requires additional field map