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Performance curves for predicting conversion from MCI to AD, comparing MCI-CPS and Raw classifier. (a) Five -fold cross-validation in ADNI-1. Solid red line: MCI-CPS (5-fold), AUC = 0.8260; dashed blue line: Raw classifier (5-fold), AUC = 0.7849. (b) Performance of model with ADNI-GO/2 as an independent test set. Solid red line: MCI-CPS, AUC = 0.7809; dashed blue line: Raw classifier, AUC = 0.7646.
