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. 2021 May 21;9(6):587. doi: 10.3390/biomedicines9060587

Table 6.

Summary of apolipoprotein mimetic peptides known to have an effect on immune cell function.

Specific Apolipoprotein
Mimetic Peptides
Number of Residues Amino Acid Sequence References
ApoA-I mimetic peptides
4F peptide 18 Ac-D-W-F-K-A-F-Y-D-K-V-A-E-K-F-K-E-A-F-NH2 [299,300]
D-4F peptide 18 Ac-D-W-F-K-A-F-Y-D-K-V-A-E-K-F-K-E-A-F-NH2 [301]
L-4F peptide 18 Ac-D-W-F-K-A-F-Y-D-K-V-A-E-K-F-K-E-A-F-NH2 [302]
5A peptide 37 D-W-L-K-A-F-Y-D-K-V-A-E-K-L-K-E-A-F-P-D-W-A-K-A-A-Y-D-K-A-A-E-K-A-K-E-A-A [301]
ApoE mimetic peptides
Ac-hE18A-NH2 28 Ac-L-R-K-L-R-K-R-L-L-R-D-W-L-K-A-F-Y-D-K-V-A-E-K-L-K-E-A-F-NH2 [106]

Summary of the apolipoprotein mimetic peptides known to have an effect on immune cell function. Abbreviations: apoA-I—apolipoprotein A-I; apoE—apolipoprotein.