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. 2021 May 21;11(6):928. doi: 10.3390/diagnostics11060928

Table 2.

Characteristics of SOS/VOD patients.

Patient Gender Age HSCT Type Conditioning Regimen Underlying Disease Baseline 2D-SWE (m/S) Baseline 2D-SWE (kPa) Baseline PV Velocity (cm/S) Clinical SOS/VOD Diagnosis † Serum Bilirubin >2 mg/dL at Diagnosis SWE at SOS/VOD Diagnosis (m/S) SWE at SOS/VOD Diagnosis (kPa) Max. Increase in SWE (m/S; kPa) Max. SWE (m/S; kPa) Ascites in US Decreased/Reversed PV Flow Gallbladder Wall Thickening Date of US/SWE SOS/VOD Severity † Max. Bilirubin (mg/dL) SOS/VOD Therapy Outcome SWD ((m/S)/kHz); (day)
1 male 36 allogenic (MMUD) 4 × 3.2 mg/kg busulfan, 2 × 60 mg/kg cyclophosphamide AML 1.42 5.9 29 +18 3.26 4.17 58.8 2.75; 52.9 4.17; 58.8 yes ‡ yes yes +18 severe 34.71 DEF, diuretics Death (+110) 16.7 (+20)
2 female 64 allogenic (MUD) treosulfan, fludarabine, thiothepa MM 1.26 4.7 29 +18 5.62 1.71 8.9 0.52; 5 1.78; 9.8 no no no +19 severe 20.76 DEF, diuretics death (+63) 17.2 (+54)
3 male 45 allogenic (MUD) 4 × 3.2 mg/kg busulfan, 2 × 60 mg/kg cyclophosphamide CML 1.20 4.2 16 +21 4.46 2.11 13.9 2.52; 41.3 3.72; 45.5 yes ‡ yes yes +47 severe 35.83 DEF, diuretics death (+78) 20.9 (+47)

Abbreviations: MUD, matched unrelated donor; MMUD, mismatch unrelated donor; AML, acute myeloid leukemia; MM, multiple myeloma; PV, portal vein; † according to Mohty et al. 2016 [7]; US, ultrasound; DEF, defibrotide; SWE, shear wave elastography; SWD, shear wave dispersion. ‡ Small amounts of ascites, no detection of ascites in the area of 2D-SWE measurement.