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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Drug Alcohol Depend. 2020 Oct 20;218:108348. doi: 10.1016/j.drugalcdep.2020.108348

Figure 3:

Figure 3:

Effectiveness and time course of a fentanyl vaccine to attenuate choice between fentanyl and food in rhesus monkeys (n=3–5). Panel A ordinate: percent fentanyl choice. Panel A abscissa: unit fentanyl dose in micrograms per kilogram per injection. Panel B ordinate: choices per session. Panel B abscissa: Reinforcer type. Bottom ordinate (C): session percent fentanyl choice. Bottom abscissa: experimental week. Points and bars in panels A and B represent mean ±SEM obtained during days 5–7 of each 7-day treatment period. For panel C, filled symbols represent mean ±SEM and open symbols represent individual subject data. Asterisks denote significantly different from saline treatment “baseline” (p<0.05).