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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Drug Alcohol Depend. 2020 Oct 20;218:108348. doi: 10.1016/j.drugalcdep.2020.108348

Figure 4:

Figure 4:

Time course of fentanyl antibody levels and affinity measures in rhesus monkeys (n=5). Panel A shows fentanyl antibody levels in the blood in micrograms per milliliter as a function of experimental week. Panel B shows fentanyl antibody affinity (IC50 values, nM) measures as a function of experimental week. Filled symbols represent mean ±SEM and open symbols represent individual subject data.