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. Author manuscript; available in PMC: 2021 Jun 24.
Published in final edited form as: Cancer. 2020 Jul 14;126(18):4126–4135. doi: 10.1002/cncr.32960

Table 2.

Oncogenic Mutations

Gene cDNA Amino Acid
APC c.1585C>T p.L529F
ARID1A c.5202T>G p.Y1734*
ATR c.4430C>G p.P1477R
BCOR c.2360C>T p.P787L
BRD4 c.886A>C p.T296P
CHEK1 c.1235T>C p.V412A
CHEK2 c.680G>A p.G227E
CIC c.89G>A p.R30H
CTNNB1 c.1004A>T p.K335I
CTNNB1 c.122C>T p.T41I
DIS3 c.2417A>G p.D806G
EIF4A2 c.881A>G p.H294R
EPHA5 c.2382G>C p.M794I
ERBB3 c.621_622delinsCC p.K207_T208delinsNP
FAT1 c.12791C>T p.S4264L
GRIN2A c.3211C>A p.H1071N
HGF c.1504C>G p.R502G
INPP4B c.7delA p.I3fs
KMT2C c.8539G>A p.D2847N
KRAS c.356A>G p.D119G
MED12 c.6118G>T p.A2040S
MPL c.1586G>A p.W529*
NCOR1 c.4556delC p.S1519*
NKX3-1 c.225G>C p.Q75H
NOTCH1 c.3340C>T p.R1114C
NOTCH3 c.6743C>T p.S2248F
NSD1 c.6531G>A p.M2177I
KTRK2 c.1784A>G p.D595G
PAK7 c.996T>A p.D332E
RASA1 c.143C>A p.P48H
ROS1 c.377G>A p.G126E
SF3B1 c.1447G>T p.D483Y
SF3B1 c.674G>T p.G225V
SYK c.1850C>A p.P617H
TERT g.1295228C>T
TET1 c.5973T>A p.D1991E
WT1 c.811C>A p.H271N
YAP1 c.370C>G p.R124G
ZFHX3 c.3195G>C p.E1065D

Abbreviation: cDNA, complementary DNA.

*

Means Substitution - Nonsense.