Table 2.
Comparison of biomarkers between DCM patients, stratified according to LGE and ECV.
| Without LGE (n = 56) |
With LGE (n = 44) |
p-Value | ECV ≤ Median (n = 50) |
ECV > Median (n = 50) |
p-Value | |
|---|---|---|---|---|---|---|
| NT-proBNP (pg/mL) | 345 (109.5–1047) | 972 (432–1818) | <0.001 | 389 (81- 793.5) | 1371 (750–2652) | <0.001 |
| hsTnT (ng/mL) | 0.007 (0.005–0.014) | 0.013 (0.009–0.02) | <0.001 | 0.009 (0.007–0.018) | 0.013 (0.007–0.02) | <0.001 |
| CT-1 (pg/mL) | 42.3 (6.1–169.2) | 81.9 (4.9–225.1) | 0.81 | 60.3 (6.1–189) | 37.1 (4.9–225.1) | 0.69 |
| PDGF-BB (pg/mL) | 254.7 (139.3–334.3) | 215.4 (135–362) | 0.36 | 221.6 (133–334) | 216.8 (139–331) | 0.95 |
| GDF-15 (pg/mL) | 26.5 (18.3–47.1) | 28.3 (20.3–60.9) | 0.67 | 24.9 (18.1–40.8) | 33.7 (23.3–60.3) | 0.08 |
| PICP (ng/mL) | 95.5 (65.7–173.4) | 75.8 (68.4–204) | 0.72 | 97.7 (71.7–306) | 77.1 (65.7–146) | 0.09 |
| PIIINP (ng/L) | 161.2 (127.9–350.5) | 163.9 (135–445) | 0.79 | 165.5 (129–571) | 157 (127.9–309) | 0.26 |
| CTIP (ng/mL) | 0.32 (0.22–0.38) | 0.28 (0.22–0.34) | 0.91 | 0.28 (0.21–0.35) | 0.29 (0.23–0.35) | 0.41 |
Abbreviations: NT-proBNP—N-terminal fragment of the prohormone B-type natriuretic peptide, hsTnT—high-sensitive troponin T, CT-1—cardiotrophin-1, GDF-15—growth/differentiation factor-15, PDGF-BB—platelet-derived growth factor subunit B, PICP—procollagen I C-terminal propeptide, PIIINP—procollagen III N-terminal propeptide, CTPI—terminal telopeptides of type I collagen (CTPI).